Rapidly advancing studies on rhodopsin have focused on new strategies for crystallization of this integral membrane protein for x-ray analysis and on alternative methods for structural determination from nuclear magnetic resonance data. Functional studies of the interactions between the apoprotein and its chromophore have clarified the role of the chromophore in deactivation of opsin and in photoactivation of the pigment.

Understanding terrestrial carbon metabolism is critical because terrestrial ecosystems play a major role in the global carbon cycle. Furthermore, humans have severely disrupted the carbon cycle in ways that will alter the climate system and directly affect terrestrial metabolism. Changes in terrestrial metabolism may well be as important an indicator of global change as the changing temperature signal. Improving our understanding of the carbon cycle at various spatial and temporal scales will require the integration of multiple, complementary and independent methods (...) that are used by different research communities. Tools such as air sampling networks, inverse numerical methods, and satellite data allow us to study the strength and location of the global- and continental-scale carbon sources and sinks. Bottom-up studies provide estimates of carbon fluxes at finer spatial scales and examine the mechanisms that control fluxes at the ecosystem, landscape, and regional scales. Bottom-up approaches include comparative and process studies that provide the necessary mechanistic information to develop and validate terrestrial biospheric models. An iteration and reiteration of top-down and bottom-up approaches will be necessary to help constrain measurements at various scales. We propose a major international effort to coordinate and lead research programs of global scope of the carbon cycle. (shrink)

When Vladimir Umanets entered the Tate Modern on October 7, 2012 and defaced Rothko's Black on Maroon, he was operating, not as an artist or a vandal, but as a Yellowist. Yellowism is neither art nor anti-art but is instead a supposedly new cultural element that exists for its own sake and is about nothing but the color yellow. It might be tempting to write Yellowism and the Rothko defacement off as a mere prank or as pseudo-intellectual fraud, but I (...) argue that, intentionally or not, the Yellowists have raised salient issues salient to those invested in both the ontology of art and social ontology more generally. In particular, their actions highlight issues pertaining to the relationship between stipulation and ontology. I explore these issues in this paper. (shrink)

Rationale, aims and objectives This randomized controlled trial was designed to evaluate the 2-year costs and effects of a proactive, public health nursing case management approach compared with a self-directed approach for 129 single parents (98% were mothers) on social assistance in a Canadian setting. A total of 43% of these parents had a major depressive disorder and 38% had two or three other health conditions at baseline. Methods Study participants were recruited over a 12 month period and randomized into (...) two groups: one receiving proactive public health nursing and one which did not. Results At 2 years, 69 single parents with 123 children receiving proactive public health nursing (compared with 60 parents with 91 children who did not receive public health nursing services) showed a slightly greater reduction in dysthymia and slightly higher social adjustment. There was no difference between the public health and control groups in total per parent annual cost of health and support services. However, costs were averted due to a 12% difference in non-use of social assistance in the previous 12 months for parents in the public health nursing group. This translates into an annual cost saving of $240 000 (Canadian) of costs averted within 1 year for every 100 parents. Conclusions In the context of a system of national health and social insurance, this study supports the fact that it is no more costly to proactively service this population of parents on social assistance. (shrink)

Eighteenth-century England saw the rise of a "peculiarly English" art form—landscape gardening—and a corresponding change in attitudes toward the antural world. While the French, who lived under tyranny, had a tightly organized, restrictive gardens, the "free" English enjoyed gardens where they were at liberty to wander. John Dixon Hunt examines eighteenth-century letters, literary and critical works, biographies, paintings, prints, and drawings to trace the gradual movement from formal regularity toward a carefully calculated naturalness.

In disputes about the ontology of music, musical idealism—that is, the view that musical compositions are ideas—has proven to be rather unpopular. We argue that, once we have a better grip on the ontology of ideas, we can formulate a version of musical idealism that is not only defensible, but plausible and attractive. We conclude that compositions are a particular kind of idea: they are completed ideas for musical manifestation.

Compares and contrasts the ethical systems derived from the major religions of the world.

Participants recruited for high levels of imaginative absorption were administered a questionnaire based on Calkins' original study that first established a wide continuum of childhood synaesthesias and synaesthetic associations, along with separate questionnaires assessing childhood imaginary companions, positive altered states of consciousness and negative states of nightmares and night terrors. Their inter-relation and relation to measures of adult imaginative absorption helps to establish these states as aspects of an underlying imagistic dimension, while their relative differentiation is explored through different forms (...) of adult absorption, early stressors from childhood, and degree of parental support for creative activities. The connection of this wider continuum of adult recalled childhood synasesthesias, imaginary companions, and altered states of consciousness to adult imaginative absorption is consistent with recent neuro-imaging synaesthetic research supporting its relation to symbolic cognition, metaphor, and creativity. (shrink)

Peter Goldie and Elisabeth Schellekens have recently articulated the Idea Idea, the thesis that “in conceptual art, there is no physical medium: the medium is the idea.” But what is an idea, and in the case of works such as Duchamp's Fountain, how does the idea relate to the urinal? In answering these questions, it becomes apparent that the Idea Idea should be rejected. After showing this, I offer a new ontology of conceptual art, according to which such artworks are (...) not ideas but artifacts imbued with ideas. After defending this view from objections, I briefly discuss some implications it has for the ontology of art in general. (shrink)

Stephen Davies’s Adornment lays an admirable foundation upon which much fruitful philosophical discussion about the topic of adornment can—and likely, will—be b.

Some artworks—works of music, theatre, dance, and the like—are works for performance. Some works for performance are, I contend, unperformable. Some such works are unperformable by beings like us; others are unperformable given our laws of nature; still others are unperformable given considerations of basic logic. I offer examples of works for performance—focusing, in particular, on works of music—that would fit into each of these categories, and go on to defend the claim that such ‘works’ really are genuine works, musical (...) works and works for performance. I then argue that the very possibility of such works is ontologically significant. In particular, the possibility of these works raises serious problems for type-theoretic accounts of the ontology of music as well as certain mereological or constitution-based accounts. (shrink)

Philosophers often talk about and engage with ideas. Scientists, artists, and historians do, too. But what is an idea? In this paper, we first motivate the desire for an ontology of ideas before discussing what conditions a candidate ontology would have to satisfy to be minimally adequate. We then offer our own account of the ontology of ideas, and consider various strategies for specifying the underlying metaphysics of the account. We conclude with a discussion of potential future work to be (...) done on the ontology of ideas. (shrink)

At first glance, the properties being omniscient and being worthy of worship might appear to be perfectly co-instantiable. But there are reasons to be worried about this co-instantiability, as it turns out that, depending on our commitments with respect to certain kinds of knowledge and notions of personhood, it might be the case that no being—God included—could instantiate both. In this paper, I lay out and motivate this claim before going on to consider a variety of responses—some more plausible than (...) others—that may be offered by the theist. (shrink)

Aaron Smuts has argued that attempts to offer a plausible distinction between stories and tellings will likely face insurmountable difficulties. Here, I offer a distinction between stories and tellings that does not face these difficulties. In doing so, I propose an ontology of stories according to which such entities are ideas for narrative manifestation. In developing this ontology, I also consider parallels between stories and musical compositions.

According to David Lewis, many de re modal predications – that is, sentences such as ‘John McCain could have won the 2008 U.S. Presidential election’ and ‘Dwight could receive a promotion’ – are inconstant insofar as their truth values can vary alongside changes in our interests. In this paper, I argue that previous accounts of this inconstancy, such as those offered by Lewis and Harold Noonan, are inadequate. Linguistic data, I claim – specifically, agreement and disagreement data – tell against (...) these views and in favor of a new, more radical approach. My goal in this paper is to present such data in an effort to offer some initial motivation for this new approach. (shrink)

Drawing from Goffman’s original observations on stigma and the consequences of interactions between the stigmatized and supportive or stigmatizing audiences, we conduct a 20-year review of the diverse literature on stigma to revisit the collective nature of stigmatization processes. We find that studies on stigma’s origins, responses, processes, and outcomes have diverged from Goffman’s relational view of stigma as they have overlooked important relational mechanisms explaining the processes of (de)stigmatization. We draw from those conclusions to justify the need to study (...) stigma as a collective phenomenon. We develop a relational perspective on stigma based on understanding how attributes are stigmatized (or not) by audiences in their interactions. We argue that to advance stigma research, it is necessary to build on Goffman’s theory to include the stigmatizers (i.e., the normal) and supporters (i.e., the wise); how they create, sustain, or remove stigma; and how they relate to the stigmatized (i.e., the targets). Accordingly, we provide a research agenda on stigma as a collective phenomenon that theorizes a relational perspective, proposes a typology of how audiences relate to stigmatization, and identifies patterns of relations between audiences. We thus offer a missing piece to existing accounts of stigma by focusing on the key role of audiences (i.e., stigmatizers or supporters of the stigmatized) rather than on the targets of stigma (i.e., the own). (shrink)

Personal and social norms are well-established predictors of proenvironmental behavior, and past research often discusses the motivational properties of different norms. However, less research has examined how individuals feel after conforming to, or deviating from, a norm. We suggest that emotions may function as norm enforcement tools that reward conformity and punish deviance. As a starting point, we outline the emotions that individuals may experience when conforming to, or deviating from, different norms (i.e., personal norms, descriptive social norms, injunctive social (...) norms), and how these emotions can influence proenvironmental behavior. More research is needed to clarify how emotions facilitate, and possibly mediate, the influence of norms on proenvironmental behavior. (shrink)

A method is given to determine whether or not the distribution functions describing the two spin measurements in the spin-s Einstein-Podolsky-Rosen experiment are compatible with the existence of distributions describing three spin measurements (not all of which can actually be performed). When applied to the spin-1/2 case the method gives the results of Wigner, or of Clauser, Holt, Horne, and Shimony, depending on whether or not the two-spin distributions are assumed to have the forms given by the quantum theory. Generalizations (...) of the conditions of Wigner or of Clauser et al. to the spin-1 case are explicitly calculated. The spin-3/2 case is examined in some simple geometries to show that an apparently monotonic trend toward local realism as s increases from1/2 to1 is, in fact, violated when s increases from1 to3/2. The analysis is based on a novel representation of the modulus squared of a rotation matrix element. The structure of that matrix element responsible for the restoration of local realism in the classical (large s) limit is identified, but a rigorous treatment of the classical limit is not attempted. The higher-spin results are significantly stronger than those given by Mermin's spin-s Bell inequality. (shrink)

In this paper, we discuss a team-taught, debate-style Philosophy of Religion course we designed and taught at The Ohio State University. Rather than tackling the breadth of topics traditionally subsumed under the umbrella of Philosophy of Religion, this course focused exclusively on the nuances of the atheism-theism debate, with the instructors openly identifying as atheist or theist, respectively. After discussing the motivations for designing and teaching such a course, we go on to detail its content and structure. We then examine (...) various challenges and hurdles we faced, as well as some benefits we encountered along the way. Next, we discuss some informal data collected from the students enrolled in the course, some of which suggest some rather surprising outcomes. We conclude with some considerations of the applicability of this style of teaching to other philosophical debates. (shrink)

Ramsey et al. attempt to clarify methodological issues for identifying innovative behaviour. Their effort is seriously weakened by an underlying presumption that the behavior of primates is generally learned and that of non-primates is generally This presumption is based on a poor grasp of the non-primate literature and a flawed understanding of how learned behaviour is genetically assimilated.

This article explores whether theory-ladenness makes empirical testing an inse cure foundation for objectivity. Specifically, this article uses path diagrams as visual heuristics to assist in (1) developing a parsimonious representation of the traditional empiricist view of empirical testing, (2) showing how the "New Image" view ostensibly threatens the objectivity of science, (3) proposing a unified, realist theory of empirical testing, (4) developing a representation of the unified theory, (5) exploring several potential threats to objectivity, (6) discussing the proposed theory's (...) implications for social science, and (7) adumbrating three foundational premises for scientific realism. (shrink)

The concept of evolvability—the capacity of a population to produce and maintain evolutionarily relevant variation—has become increasingly prominent in evolutionary biology. Paleontology has a long history of investigating questions of evolvability, but paleontological thinking has tended to neglect recent discussions, because many tools used in the current evolvability literature are challenging to apply to the fossil record. The fundamental difficulty is how to disentangle whether the causes of evolutionary patterns arise from variational properties of traits or lineages rather than being (...) due to selection and ecological success. Despite these obstacles, the fossil record offers unique and growing sources of data that capture evolutionary patterns of sustained duration and significance otherwise inaccessible to evolutionary biologists. Additionally, there exist a variety of strategic possibilities for combining prominent neontological approaches to evolvability with those from paleontology. We illustrate three of these possibilities with quantitative genetics, evolutionary developmental biology, and phylogenetic models of macroevolution. In conclusion, we provide a methodological schema that focuses on the conceptualization, measurement, and testing of hypotheses to motivate and provide guidance for future empirical and theoretical studies of evolvability in the fossil record. (shrink)

Attributions of omnipresence, most familiar within the philosophy of religion, typically take the omnipresence of an entity to either consist in that entity's occupation of certain regions or be dependent upon other of that entity's attributes, such as omnipotence or omniscience. This paper defends an alternative conception of omnipresence that is independent of other purported divine attributes and dispenses with occupation. The resulting view repurposes the metaphysics of necessitism and permanentism, taking omnipresent entities to be those entities that exist at (...) all regions. This view is then shown to best accommodate attributions of omnipresence to a diverse range of metaphysical posits, like abstract entities, and a more diverse class of religious posits. (shrink)

Abstract:This study explores a phenomenon that has been shown to adversely affect managers’ decisions—competitive irrationality. Managers are irrationally competitive in their decisions when they focus on damaging the profits of competitors, rather than improving their own profit performance. Studies by Armstrong and Collopy (1996) and Griffith and Rust (1997) suggest that the phenomenon is common but not universal. We examine the question of why some individuals exhibit competitive irrationality when making decisions, while others do not by focusing on four aspects (...) of moral philosophy—deontological orientation, cognitive moral development, idealism, and relativism. Results suggest that individuals high in deontological orientation, high in cognitive moral development, high in idealism, and low in relativism will be less competitively irrational than those who are not. (shrink)

The concept of approximate truth plays a prominent role in most versions of scientific realism. However, adequately conceptualizing ?approximate truth? has proved challenging. This article argues that the goal of articulating the concept of approximate truth can be advanced by first investigating the processes by which science accords theories the status of accepted or rejected. Accordingly, this article uses a path diagram model as a visual heuristic for the purpose of showing the processes in science that are involved in determining (...) a theory's status. This ?inductive realist? model of theory status then serves as a starting point for explicating an inductive realist view of approximate truth that, it is argued, can explain instances of the success of science, but does not (1) require science's theories to be strictly true in any world or (2) require a metric for measuring how close an approximately true theory is to some strictly true theory. To show the advantages of the inductive realist approach to approximate truth, an example of a major success story of science, the successful eradication of smallpox, is reviewed and then explained. (shrink)

We recently conducted a Quebec-wide postal survey designed to assess major stakeholders’ attitudes toward extending medical assistance in dying (MAiD) to non-competent patients with dementia. This paper reports the results of qualitative analyses of the comments left by the respondents at the end of the questionnaire. The questionnaire was mailed to randomly selected representatives of four stakeholder groups: adults 65 years old and over (n=621), informal caregivers of persons with dementia (n=471), nurses (n=514) and physicians (n=653) caring for such patients (...) at the time of the survey. A total of 1,050 questionnaires were returned, of which 420 included comments. Comments were coded into categories, themes and subthemes, and the frequency of categories compared across the four stakeholder groups. Coding enabled identification of 23 themes and five sub-themes clustered into seven major thematic categories. These relate to: 1) the respondent, 2) the survey and questionnaire, 3) persons with dementia, 4) their informal caregivers, 5) the healthcare system, 6) the legal framework governing end-of-life care, and 7) society in general. These categories were identified in all stakeholder groups, although to a varying degree for five of the seven categories. This study highlights the host of factors that may influence a person’s attitude toward extending MAiD to non-competent patients with dementia. It also illustrates how making systematic use of free-text comments can provide valuable insight into attitudes toward complex social policy issues and extend understanding of postal survey findings. (shrink)

Ammianus Marcellinus, by common consent the last great historian of Rome, rounds off his obituary notice of the emperor Constantius II with the following observation: The plain simplicity of Christianity he obscured by an old woman's superstition; by intricate investigation instead of seriously trying to reconcile, he stirred up very many disputes, and as these spread widely he nourished them with arguments about words; with the result that crowds of bishops rushed hither and thither by means of public mounts on (...) their way to synods , and while he tried to make all their worship conform to his own will, he cut the sinews of the public transport service. This is a perceptive judgement of the ecclesiastical politics of the reign of Constantius, remarkable in a pagan writer, and of exceptional significance in that it lies outside those very ‘arguments about words’ which contaminate all the Christian assessments of this emperor. Although Ammianus is unsympathetic to Constantius, he manages succinctly to grasp the basic drift of imperial policy, inherited from Constantine himself, of trying to enforce the emperor's view of doctrinal and ecclesiastical unity by the summoning of repeated episcopal councils and browbeating the bishops into agreement — thus paying lip-service to the independence of the church's judgements. To the observant outsider, this process was notable above all for the burden it placed on the cursus publicus, as the bishops went about their business around the empire now provided with official evectiones; and Ammianus' comment finds confirmation in the letter issued by eastern bishops attending one of the many councils of Constantius' reign, that at Sardica in 343, who complained of the ‘attrition’ of the transport service caused by the imperial summons. (shrink)